Analysis of ROR1 Protein Expression in Mice with Reconstituted Human Immune System Components
نویسندگان
چکیده
منابع مشابه
Viral infections in mice with reconstituted human immune system components.
Pathogenic viruses are often difficult to study due to their exclusive tropism for humans. The development of mice with human immune system components opens the possibility to study those human pathogens with a tropism for the human hematopoietic lineage in vivo. These include HCMV, EBV, KSHV, HIV, HTLV-1, dengue virus and JC virus. Furthermore, some human pathogens, like HSV-2, adenovirus, HCV...
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The human γ-herpesviruses Epstein-Barr virus (EBV or HHV4) and Kaposi sarcoma-associated herpesvirus (KSHV or HHV8) are each associated with around 2% of all tumors in humans worldwide. However, investigations into their infection, oncogenesis, and immune responses that protect from the associated tumors have been hampered by the exclusive tropism of these pathogens for humans. Mice with recons...
متن کاملHuman NK cells of mice with reconstituted human immune system components require preactivation to acquire functional competence.
To investigate human natural killer (NK)-cell reactivity in vivo we have reconstituted human immune system components by transplantation of human hematopoietic progenitor cells into NOD-scid IL2Rγ(null) mice. We demonstrate here that this model allows the development of all NK-cell subsets that are also found in human adult peripheral and cord blood, including NKp46(+)CD56(-) NK cells. Similar ...
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Background: Black seed (Nigella sativa L.) in traditional medicine is well known that the chemical composition of the immune system with many applications in traditional medicine to fight the infection. This study investigated the effect of the plant's role in the immune system and blood protein. Experimental: In this study male mice of Balb/c strain were divided into four groups test...
متن کاملEffect of hydroalcoholic extract of Nigella sativa L. on the immune system and blood protein components in mice
Background: Black seed (Nigella sativa L.) in traditional medicine is well known that the chemical composition of the immune system with many applications in traditional medicine to fight the infection. This study investigated the effect of the plant's role in the immune system and blood protein. Experimental: In this study male mice of Balb/c strain were divided into four groups test...
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ژورنال
عنوان ژورنال: Journal of Immunology Research
سال: 2018
ISSN: 2314-8861,2314-7156
DOI: 10.1155/2018/2480931